Scientist/Associate Scientist, Protein – Early Research

SUMMARY:

This role will be responsible for developing new assays and testing activities relating to selection of gene therapy candidates from AAV vectors in vitro. In this role the individual will develop cell-based assays methods for quantifying the expression and function of candidate viral vectors and their expression, in addition to characterizing the properties of the therapeutic proteins.

ESSENTIAL FUNCTIONS:

• Develop Cell-based assays to quantify the expression and function of protein produced from transduced cells
• Conduct in vitro evaluation of AAV vectors to enable the selection of vectors for in vivo testing
• Develop functional assays for expressed using appropriate in vitro models
• Collaborate with other scientists to identify areas of improvement
• Evaluate new assay technologies and innovate novel assay/methodologies strategies
• Keep good lab notebook and experiment records; Authoring of reports and protocols as needed
• Collaborate with other scientists and routinely present data
• Perform other duties as necessary

EDUCATION:

• BS or equivalent with 5+ years relevant experience, MS degree or equivalent with 3+ years relevant experience, PhD or equivalent with 1-3 years relevant experience

SKILLS AND REQUIREMENTS:

• Experience with ELISA, SDS-PAGE, Western blots, immunoassays, and other protein characterization techniques
• Experience with developing cell-based assays to determine functionality of expressed proteins
• Experience with mammalian cell culture
• Experience with flow cytometry, microscopy, and plate-based assays
• Sound understanding of statistical methods/tools for data analysis
• Excellent organizational and planning skills
• Experience in working in a multi-disciplinary team environment
• Excellent written and oral communication skills
• Adaptable to change

Level and compensation will be competitive and commensurate with experience.

All interested applicants should send a cover letter and resume to [email protected]